Ascorbate promotes carbon tetrachloride

Ascorbate promotes carbon tetrachloride

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JIN-KYU PARK DVM, PhD Kyungpook National

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Transgenic rats carrying copies of the human c-Ha-ras

Introduction Various kinds of transgenic and knockout mice have proved to be good animal models for analysis of gene functions. In the chemical carcinogenesis field, transgenic mice carrying human c-Ha-ras proto-oncogenes (rasH2 mice) have been shown to be highly susceptible to various carcinogens (16).).

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The Mammary Gland Carcinogens: The Role of Metal

The increased rate of breast cancer incidences especially among postmenopausal women has been reported in recent decades. Despite the fact that women who inherited mutations in the BRCA1 and BRCA2 genes have a high risk of developing breast cancer, studies have also shown that significant exposure to certain metal compounds and organic solvents also increases the risks of mammary gland ...

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Nrf2 and Cancer - Nrf2

Sodium ascorbate significantly attenuated HCC-induced reduction in the expression of NrF2 associated with a reduction in concentrations of hydrogen peroxide and superoxide anion. In addition, sodium ascorbate blocked HCC-induced increase in the expression

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Ascorbate promotes carbon tetrachloride-induced

Read "Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation, The Journal of Nutritional Biochemistry" on DeepDyve, the largest online rental service for scholarly research with

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Evaluation of Extracts and Isolated Fraction from Capparis

Hepatoprotective potential of Saraca ashoka (Roxb.) De Wilde bark by carbon tetrachloride induced liver damage in rats. Bulletin of Faculty of Pharmacy, Cairo University 2015, 53, 23-28. DOI: 10.1016/j.bfopcu.2014.11.002. Ezgi Durmaz, Gulum

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Research Article ISSN : 0975-7384 CODEN(USA) : JCPRC5

rum Aureum, Hill-Growing Saltwort Herb, Fumaria Schleicheri and Cynara scolymus on carbon tetrachloride-induced oxidative stress in vitro and in vivo. It was observed, that administration of plant extracts to rats signifi-cantly improve the oxidant status in blood

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Flavonoid boosts antioxidant power of Vitamin C - - Life

Many chemicals used for industrial and commercial purposessuch as dioxins, dibenzofurans, and carbon tetrachlorideact like poisons in the liver. Some can induce liver toxicity and hepatitis by promoting the peroxidation of lipids. 46 Through its powerful antioxidant effects, dihydroquercetin may protect the liver against both toxic exposure and viral infection.

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Growth, physiological and molecular traits in Salicaceae

A similar or even slightly higher (35%) carbon percentage can be estimated for trees, including some Populus spp. (Grayston et al. 1997). The amount of released carbon is one of the more likely reasons that make these plants good hosts of microorganisms in

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Phenol Antioxidant Quantity and Quality in Foods: Fruits

Ascorbate had only a minor contribution to the antioxidants in fruits with the exception of melon, nectarine, orange, white grape, and strawberry. The fruit extracts' antioxidant quality was better than the vitamin antioxidants and most pure phenols, suggesting synergism among the antioxidants in the mixture.

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Superoxide Ion: Generation and Chemical Implications

Superoxide ion (O2•) is of great significance as a radical species implicated in diverse chemical and biological systems. However, the chemistry knowledge of O2• is rather scarce. In addition, numerous studies on O2• were conducted within the latter half of the ...

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Publications - International Natural Product Sciences

Vacca RA, de Pinto MC, Valenti D, Passarella S, Marra E, De Gara L. Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell.

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Carbon Tetrachloride Degradation by Alkaline Ascorbic

The reduction performance of carbon tetrachloride (CT) mediated by carbon dioxide radical anion (CO2[rad]) was investigated in this study, and CO2[rad] was generated by the reaction of ...

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Ablation of aldehyde reductase aggravates carbon

Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and ... I.H. Hong, S.Y. Han, S.Y. You, et al.Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30 ...

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Kinetics of deamination and Cu(II)/H 2 O 2 /Ascorbate

Huachuan Cao, Yong Jiang, Yinsheng Wang, Kinetics of deamination and Cu(II)/H 2 O 2 /Ascorbate-induced formation of 5-methylcytosine glycol at CpG sites in duplex DNA , Nucleic Acids Research, Volume 37, Issue 19, 1 October 2009, Pages 66356643,

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Slc23a2 (solute carrier family 23 member 2) - Rat Genome

Homo sapiens (human) : SLC23A2 (solute carrier family 23 member 2) HGNC Alliance Mus musculus (house mouse) : Slc23a2 (solute carrier family 23 (nucleobase transporters), member 2) MGI Alliance Chinchilla lanigera (long-tailed ...

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Protective Effects of Lemon Juice on Alcohol-Induced

In previous studies, lemon flavonoid was shown to possess a hepatoprotective effect on liver damage induced by carbon tetrachloride and acute exercise, and the mechanism of the protective effect was related to the antioxidant capacity [7, 13].

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Microbial Reduction of Crystalline Iron(III) Oxides:

Quantitative aspects of microbial crystalline iron(III) oxide reduction were examined using a dissimilatory iron(III) oxide-reducing bacterium (Shewanella alga strain BrY). The initial rate and long-term extent of reduction of a range of synthetic iron(III) oxides were linearly correlated with oxide surface area. Oxide reduction rates reached an asymptote at cell concentrations in excess of ...

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Antioxidants_from_macroalgae-_Review_2010_

Scientists in Asian countries have demonstrated the health benefits derived from eating seaweeds (Nisizawa 2002), and the official Japanese Food Guide (see Rhatigan 2009 for discussion) promotes seaweed as a nutritional foodstuff.

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Ascorbate promotes carbon tetrachloride-induced

The genetic deletion of the senescence marker protein 30 (SMP30) gene results in ascorbate deficiency and the premature aging processes in mice. Apparent liver injury of SMP30 / mice was less severe than those of wild type (WT) mice, upon chronic CCl 4 injection. injection.

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Ascorbate promotes carbon tetrachloride-induced

Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation Author links open overlay panel Mi-Ran Ki a Hye-Rim Lee a Jin-Kyu Park a Il-Hwa Hong a Seon-Young Han a You a a ...

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Acute enteral manganese intoxication with hepatic failure

Approximately 612 hr prior to presentation, the dog ingested approximately 60 g of glucosamine hydrochloride (10.3 g/kg), 25 g of methylsulfonylmethane (4.3 g/kg), 30 g of sodium chondroitin sulfate (5.2 g/kg), and 500 mg of manganese ascorbate (86 mg/kg).

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Antioxidants Free Full-Text Silymarin as a Natural

Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various flavonolignans (with silybin being the major one), has received a tremendous amount of attention over the last decade as a herbal remedy for liver treatment. In many cases, the antioxidant properties of SM are considered to be responsible for its protective actions. Possible antioxidant mechanisms of ...

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Hypoxia preconditioned bone marrow mesenchymal stem

Bone marrow mesenchymal stem cells (BMMSCs) have been reported to facilitate liver regeneration after toxic injuries. However, the effect of BMMSCs on liver regeneration after massive hepatectomy is barely studied. Here we explored whether infusion of BMMSCs promotes liver regeneration in a rat massive hepatectomy model. Hypoxia preconditioning was achieved by culturing BMMSCs under a hypoxia ...

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Ascorbate promotes carbon tetrachloride-induced

Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation. Ki MR(1), Lee HR, Park JK, Hong IH, Han SY, You SY, Lee EM, Kim AY, Lee SS, Jeong KS.

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Heat-shock preconditioning reduces oxidative protein

Membrane lipids and cytosolic proteins are major targets of oxidative injury. This study examined the effect of heat-shock preconditioning associated with the induction of heat-shock protein 72 on liver injury, from the aspect of lipid peroxidation and protein denaturation after carbon tetrachloride (CCl4) administration in rats one of the representative oxidative injuries. Male Wistar ...

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Ascorbate promotes carbon tetrachloride-induced

Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation Article in The Journal of nutritional biochemistry 22(6):535 ...

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LRA by ELISA/ACT Test Results For

Ascorbate (buffered Vitamin C) Powder or tablets Depends on amount body will absorb (determined by the Ascorbate calibration protocol) Four or more times a day Central regulator of cell metabolism, a stimulant to structural connective protein synthesis, & is

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JNB The Journal of Nutritional Biochemistry Vol 22,

Read the latest articles of The Journal of Nutritional Biochemistry at ScienceDirect.com, Elseviers leading platform of peer-reviewed scholarly literature select article An increase in liver PPARγ2 is an initial event to induce fatty liver in response to a diet high in butter ...

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Mangiferin: a natural miracle bioactive compound against lifestyle

complex administration in rats treated with carbon tetrachloride through restoration of liver antioxidant and serum hepatic marker enzymes. The bioavailability of mangiferin in rats increased 9.75-fold when using the mangiferin complex compared to pure mangiferin.

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Chinese Herbal Medicine for the Treatment of Hepatitis B

Atractylodes is included in this formulation as a digestive aid, though its use can also be justified on the basis of laboratory studies showing that it protects mice from liver injury induced by carbon tetrachloride and promotes liver cell regeneration; it is also used as ...

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Seon-Young Han's research works Kyungpook National

Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation Citing article Jun

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